蛋白质液滴可能导致多种类型的遗传疾病

Protein droplets may cause many types of genetic disease

【作者】 Dr. Denes Hnisz,Prof. Dr. Denise Horn

2023-02-08
德国马普学会
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Most proteins localize to distinct protein-rich droplets in cells, also known as “cellular condensates”. Such proteins contain sequence features that function as address labels, telling the protein which condensate to move into. When the labels get screwed up, proteins may end up in the wrong condensate. According to an international team of researchers from clinical medicine and basic biology, this could be the cause of many unresolved diseases.

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