The U.S. State Department has highlighted three broad policy priorities—interconnection, innovation, and inclusion—to guide the United States during its year as host and chair of the Asia-Pacific Economic Cooperation (APEC). The Biden administration, however, has not provided high-level direction for exactly what it hopes to achieve. Thankfully, this has not stopped the United States’ highly capable economic policy officials from laying the groundwork to make its APEC host year a success. The first APEC Senior Officials’ Meeting (SOM) in Palm Springs included productive digital policy discussions. The United States should build on this momentum at SOM 2 and 3, the trade ministers meeting, and other meetings to push for a pragmatic, yet realistic, digital agenda that includes electronic invoices (e-invoices); electronic labels (e-labels); an Asia-Pacific regional data commons via data-sharing models, especially for health data; action on improving digital skills for the workforce; and cybersecurity for critical infrastructure and government services, among other measures