2023年,世卫组织(WHO)召集了一个指南制定小组,更新关于评估产后出血(PPH)的现有建议,并考虑使用护理捆绑包来治疗PPH。这一决定是基于关于这一主题的新证据。本文件发布了关于产后出血评估的最新建议,以及关于使用治疗包管理产后出血的新建议。
In order to better treat patients diagnosed with acute myeloid leukaemia (AML), researchers need to understand the pathological processes and distinguish between different subgroups of the disease. With the help of proteome and genetic analysis, researchers at the Max Planck Institute of Biochemistry in Martinsried, together with cooperation partners from the Frankfurt University Hospital, German Cancer Research Center (DKFZ) as well as German Cancer Consortium (DKTK) have discovered a new subtype. This subtype shows increased amounts of mitochondrial proteins as well as an altered mitochondrial metabolism. In laboratory tests, these so-called Mito-AML cells can be combated more effectively with inhibitors against mitochondrial respiration than with conventional chemotherapeutic agents.
Using lab-created tissue to heal or replace damaged organs is one of the great visions for the future of medicine. Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain stable in the organism long enough for the body to form new natural structures. A fundamental requirement for functional tissue is that blood vessels must be able to grow in them and connect to the organism’s vascular system, so that the tissue is properly supplied with oxygen and nutrients. However, until now, almost nothing has been known about which material properties promote the growth of blood vessels. A team headed by biomedical engineer Dr Britta Trappmann from the Max Planck Institute for Molecular Biomedicine in Münster, Germany, has developed a cell culture system in which, for the first time, a functional blood vessel system is able to grow within a framework made of synthetic materials.
特洛伊·兰德尔的新型冠状病毒感染病症状很难治,但还可以忍受。从3月下旬开始的发烧、咳嗽和头痛恢复后,他获准重返南泽西州Virtua Health Network的心脏病专家工作。但在4月中旬,兰德尔重返工作岗位两天后,他的头再次开始疼痛,而且是不同的。他觉得它就像被夹在老虎钳里一样。核磁共振显示,血液凝块堵塞了兰德尔大脑的一条动脉。他中风了。世界各地的医生开始在一些病情最严重的COVID患者中报告同样的情况,以及身体其他部位较小的血液凝块神秘增加。肺、肝、肾--甚至脚趾--就像几个月前在许多社交媒体上描述的那些略带紫色的“COVID脚趾”一样。作为预防措施,许多医院开始使用大剂量血液稀释剂治疗COVID患者。